Saturday, December 25, 2010

Sernade




Sernade may be available in the countries listed below.


Ingredient matches for Sernade



Sertraline

Sertraline hydrochloride (a derivative of Sertraline) is reported as an ingredient of Sernade in the following countries:


  • Indonesia

International Drug Name Search

Wednesday, December 22, 2010

budesonide



bue-DES-oh-nide


Commonly used brand name(s)

In the U.S.


  • Entocort EC

In Canada


  • Pulmicort

  • Pulmicort Spacer

Available Dosage Forms:


  • Capsule, Delayed Release

  • Capsule, Extended Release

Therapeutic Class: Endocrine-Metabolic Agent


Pharmacologic Class: Adrenal Glucocorticoid


Uses For budesonide


Budesonide is used to treat an inflammatory bowel disease called Crohn's disease. budesonide works inside the intestine (bowel) to reduce inflammation and symptoms of the disease. It also helps keep the symptoms of Crohn's disease from coming back. Budesonide is a steroid (cortisone-like) medicine.


budesonide is available only with your doctor's prescription.


Before Using budesonide


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For budesonide, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to budesonide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of budesonide in the pediatric population. Safety and efficacy have not been established.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of budesonide in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving budesonide.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking budesonide, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using budesonide with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Boceprevir

  • Bupropion

  • Telaprevir

Using budesonide with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Erythromycin

  • Itraconazole

  • Ketoconazole

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using budesonide with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use budesonide, or give you special instructions about the use of food, alcohol, or tobacco.


  • Grapefruit Juice

Other Medical Problems


The presence of other medical problems may affect the use of budesonide. Make sure you tell your doctor if you have any other medical problems, especially:


  • Cataracts (eye disease) or

  • Diabetes, or a family history of or

  • Glaucoma, or a family history of or

  • Hypertension (high blood pressure) or

  • Infection (e.g., bacteria, virus, fungus) or

  • Osteoporosis (thin bones) or

  • Stomach ulcer, active or history of or

  • Tuberculosis, active or history of or

  • Weakened immune system—Use with caution. May make these conditions worse.

  • Liver disease (including cirrhosis), moderate to severe—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of budesonide


Take budesonide exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not stop taking budesonide without first checking with your doctor.


budesonide comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions.


Swallow the capsule whole. Do not break, crush, chew, or open it.


Keep using budesonide for the full time of treatment, even if you begin to feel better after a few days. Do not miss any doses.


Dosing


The dose of budesonide will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of budesonide. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For oral dosage form (capsules):
    • For mild to moderate Crohn's disease:
      • Adults—9 milligrams (mg) once a day in the morning for up to 8 weeks. Your doctor may adjust your dose as needed.

      • Children—Use and dose must be determined by your doctor.


    • For prevention of symptoms of Crohn's disease from coming back:
      • Adults—6 milligrams (mg) once a day in the morning for up to 3 months. Your doctor may adjust your dose as needed.

      • Children—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of budesonide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using budesonide


It is very important that your doctor check your progress at regular visits for any problems or unwanted effects that may be caused by budesonide.


If your condition does not improve or if it become worse, check with your doctor.


Using too much of budesonide or using it for a long time may increase your risk of having adrenal gland problems. Talk to your doctor if you have more than one of these symptoms while you are using budesonide: darkening of the skin; diarrhea; dizziness; fainting; loss of appetite; mental depression; nausea; skin rash; unusual tiredness or weakness; or vomiting.


You may get infections more easily while using budesonide. Avoid people who are sick or have infections. Tell your doctor right away if you have been exposed to someone with chickenpox or measles.


Make sure any doctor or dentist who treats you knows that you are using budesonide. You may need to stop using budesonide several days before having surgery or medical tests.


Grapefruits and grapefruit juice may increase the effects of budesonide by increasing the amount of budesonide in your body. You should not eat grapefruit or drink grapefruit juice while you are taking budesonide.


Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.


budesonide Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common
  • Bruising easily

  • chills

  • colds

  • cough or hoarseness

  • fever

  • flu-like symptoms

  • sneezing

  • sore throat

Less common
  • Abdominal or stomach pain

  • bleeding after defecation

  • blurred vision

  • burning while urinating

  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

  • chest pain

  • convulsions

  • cough producing mucus

  • decreased urine

  • diarrhea

  • difficult or labored breathing

  • difficult or painful urination

  • dizziness

  • dry mouth

  • eye pain

  • fast, irregular, pounding, or racing heartbeat or pulse

  • feeling of warmth

  • general feeling of discomfort or illness

  • headache

  • heartburn

  • increase in body movements

  • increased thirst

  • increased urge to urinate during the night

  • irregular heartbeat

  • joint pain

  • loss of appetite

  • mood changes

  • muscle aches and pains

  • nausea or vomiting

  • nervousness

  • numbness or tingling in the hands, feet, or lips

  • pain or discomfort in the chest, upper stomach, or throat

  • pounding in the ears

  • rectal bleeding

  • redness of the face, neck, arms, and occasionally, upper chest

  • runny nose

  • severe constipation

  • shakiness in the legs, arms, hands, or feet

  • shivering

  • shortness of breath

  • slow or fast heartbeat

  • stomach cramps

  • sweating

  • swelling of the legs and feet

  • swelling or puffiness of the face

  • tightness in the chest

  • trouble sleeping

  • uncomfortable swelling around the anus

  • unusual tiredness or weakness

  • waking to urinate at night

  • weight gain

  • weight loss

  • wheezing

Incidence not known
  • Bulging soft spot on the head of an infant

  • change in the ability to see colors, especially blue or yellow

  • difficulty with swallowing

  • hives

  • itching

  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

  • skin rash

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Acid or sour stomach

  • belching

  • blemishes on the skin

  • heartburn

  • indigestion

  • pain or tenderness around the eyes and cheekbones

  • pimples

  • rounded or moon face

  • stomach discomfort, upset, or pain

  • stuffy nose

Less common
  • Accumulation of pus

  • agitation

  • blistering, crusting, irritation, itching, or reddening of the skin

  • change in hearing

  • changes in vision

  • cracked, dry, or scaly skin

  • cracks in the skin at the corners of mouth

  • difficulty with moving

  • dizziness or lightheadedness

  • ear drainage

  • earache or pain in the ear

  • feeling of constant movement of self or surroundings

  • hair loss or thinning of the hair

  • increased appetite

  • increased hair growth, especially on the face

  • lack or loss of strength

  • loss of memory

  • muscle pains or stiffness

  • nervousness

  • pain, swelling, or redness in the joints

  • pinpoint red or purple spots on the skin

  • problems with memory

  • redness, swelling, or soreness of the tongue

  • sensation of spinning

  • skin rash

  • skin rash, encrusted, scaly, and oozing

  • sleepiness or unusual drowsiness

  • sleeplessness

  • soreness or redness around the fingernails and toenails

  • swollen joints

  • unable to sleep

  • uterine bleeding between menstrual periods

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More budesonide resources


  • Budesonide Use in Pregnancy & Breastfeeding
  • Budesonide Drug Interactions
  • Budesonide Support Group
  • 22 Reviews for Budesonide - Add your own review/rating


  • budesonide Concise Consumer Information (Cerner Multum)

  • Budesonide Professional Patient Advice (Wolters Kluwer)

  • Budesonide Powder MedFacts Consumer Leaflet (Wolters Kluwer)

  • Budesonide Monograph (AHFS DI)

  • Entocort EC Sustained-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)

  • Entocort EC Prescribing Information (FDA)

  • Pulmicort Flexhaler Prescribing Information (FDA)

  • Pulmicort Flexhaler Concise Consumer Information (Cerner Multum)

  • Pulmicort Respules Suspension MedFacts Consumer Leaflet (Wolters Kluwer)

  • Pulmicort Turbuhaler Powder MedFacts Consumer Leaflet (Wolters Kluwer)



Compare budesonide with other medications


  • Asthma, Maintenance
  • Autoimmune Hepatitis
  • Crohn's Disease
  • Crohn's Disease, Acute
  • Crohn's Disease, Maintenance
  • Eosinophilic Esophagitis
  • Inflammatory Bowel Disease

Monday, December 20, 2010

Liprolog Mix25




Liprolog Mix25 may be available in the countries listed below.


Ingredient matches for Liprolog Mix25



Insulin Lispro

Insulin Lispro biphasic (a derivative of Insulin Lispro) is reported as an ingredient of Liprolog Mix25 in the following countries:


  • Germany

International Drug Name Search

Saturday, December 11, 2010

Levuloza




Levuloza may be available in the countries listed below.


Ingredient matches for Levuloza



Fructose

Fructose is reported as an ingredient of Levuloza in the following countries:


  • Bosnia & Herzegowina

  • Serbia

International Drug Name Search

Thursday, December 9, 2010

Biperiden


Generic Name: Biperiden (bye-PER-i-den)
Brand Name: Akineton


Biperiden is used for:

Treating Parkinson disease and other Parkinson-like disorders. It is used to treat certain side effects (eg, involuntary movements) caused by certain medicines. It may also be used for other conditions as determined by your doctor.


Biperiden is an anticholinergic. It works by helping to correct the chemical imbalance thought to cause Parkinson-type disorders.


Do NOT use Biperiden if:


  • you are allergic to any ingredient in Biperiden

  • you have narrow-angle glaucoma, narrowing of the esophagus, stomach or bowel problems (eg, blockage, ulcerative colitis, megacolon), heart problems caused by bleeding, myasthenia gravis, or difficulty urinating

Contact your doctor or health care provider right away if any of these apply to you.



Before using Biperiden:


Some medical conditions may interact with Biperiden. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have irregular heartbeat, epilepsy or seizures, an enlarged prostate, or a history of involuntary movements of the tongue, lips, face, or extremities caused by medicines

  • if you are at risk for glaucoma

Some MEDICINES MAY INTERACT with Biperiden. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Antihistamines (eg, chlorpheniramine), certain narcotics (eg, meperidine), phenothiazines (eg, chlorpromazine), tricyclic antidepressants (eg, amitriptyline), or certain antiarrhythmics (eg, quinidine) because the risk of side effects, such as dry mouth, difficulty urinating, and constipation, may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Biperiden may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Biperiden:


Use Biperiden as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Biperiden may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

  • If you miss a dose of Biperiden, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Biperiden.



Important safety information:


  • Biperiden may cause blurred vision, dizziness, lightheadedness, or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Biperiden. Using Biperiden alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • Biperiden may cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness.

  • Do not drink alcohol while you are taking Biperiden.

  • Do not become overheated in hot weather or during exercise or other activities because heatstroke may occur.

  • Sucking on sugarless hard candy, drinking fluids, or practicing good dental hygiene can relieve dry mouth.

  • Use Biperiden with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Biperiden during pregnancy. It is unknown if Biperiden is excreted in breast milk. If you are or will be breast-feeding while you are taking Biperiden, check with your doctor or pharmacist to discuss the risks to your baby.


Possible side effects of Biperiden:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Agitation; blurred vision; constipation; dizziness or lightheadedness when sitting up or standing; drowsiness; dry mouth, nose, or throat; nausea; nervousness; stomach upset.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); anxiety; behavior changes; chest pain; confusion; disorientation; exaggerated sense of well-being; fast, slow, or irregular heartbeat; flushing; hallucinations; loss of coordination; memory loss; mood or mental changes; seizures; trouble urinating.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Biperiden side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; dilated pupils; disorientation; fast breathing; fast heart rate; fever; hallucination; hot or flushed skin; hyperactivity; loss of consciousness; loss of memory; muscle incoordination; paralysis; seizures.


Proper storage of Biperiden:

Store Biperiden at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Biperiden out of the reach of children and away from pets.


General information:


  • If you have any questions about Biperiden, please talk with your doctor, pharmacist, or other health care provider.

  • Biperiden is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Biperiden. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Biperiden resources


  • Biperiden Side Effects (in more detail)
  • Biperiden Use in Pregnancy & Breastfeeding
  • Biperiden Drug Interactions
  • Biperiden Support Group
  • 0 Reviews for Biperiden - Add your own review/rating


  • Biperiden Professional Patient Advice (Wolters Kluwer)

  • biperiden Concise Consumer Information (Cerner Multum)

  • biperiden Advanced Consumer (Micromedex) - Includes Dosage Information

  • Biperiden Hydrochloride Monograph (AHFS DI)



Compare Biperiden with other medications


  • Extrapyramidal Reaction
  • Parkinson's Disease

Thursday, December 2, 2010

Bupropion



Pronunciation: bue-PROE-pee-on
Generic Name: Bupropion
Brand Name: Wellbutrin

Antidepressants may increase the risk of suicidal thoughts or actions in children, teenagers, and young adults. However, depression and certain other mental problems may also increase the risk of suicide. Talk with the patient's doctor to be sure that the benefits of using Bupropion outweigh the risks.


Bupropion contains the same ingredient that is in Zyban, a medicine used to help certain patients stop smoking. Some patients using bupropion to help them stop smoking have also developed depression and certain other mental or mood problems, including suicidal thoughts or actions.


Family and caregivers must closely watch patients who take Bupropion. It is important to keep in close contact with the patient's doctor. Contact the doctor at once if new, worsened, or sudden symptoms such as agitation, hostility, depressed mood, or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur. Discuss any questions with the patient's doctor.





Bupropion is used for:

Treating depression. It may also be used for other conditions as determined by your doctor.


Bupropion is an antidepressant. It works in the brain to treat depression. Exactly how it works is not known.


Do NOT use Bupropion if:


  • you are allergic to any ingredient in Bupropion

  • you are taking any other medicine that contains bupropion

  • you have a history of an eating disorder (eg, anorexia, bulimia) or seizures (eg, epilepsy)

  • you are suddenly stopping the use of alcohol or sedatives (eg, benzodiazepines) after long-term use

  • you are taking or have taken linezolid, methylene blue, or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Video: Treatment for Depression







Treatments for depression are getting better everyday and there are things you can start doing right away.






Before using Bupropion:


Some medical conditions may interact with Bupropion. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you or a family member has a history of bipolar disorder (manic depression), other mental or mood problems (eg, depression), suicidal thoughts or attempts, or alcohol or substance abuse

  • if you have diabetes, kidney problems, liver problems (eg, cirrhosis), high blood pressure, heart problems (eg, congestive heart failure), or a recent heart attack

  • if you have a history of seizures, a head injury, or a tumor in the brain or spinal cord

  • if you are taking nonprescription weight loss medicines or stimulants

Some MEDICINES MAY INTERACT with Bupropion. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Amantadine, other antidepressants (eg, amitriptyline, fluvoxamine), antipsychotics (eg, haloperidol, risperidone), clopidogrel, corticosteroids (eg, prednisone), cyclophosphamide, HIV protease inhibitors (eg, nelfinavir), insulin, levodopa, linezolid, MAOIs (eg, phenelzine), methylene blue, nicotine patches, oral hypoglycemics (eg, glipizide), orphenadrine, sympathomimetics (eg, pseudoephedrine), theophylline, thiotepa, tiagabine, or ticlopidine because they may increase the risk of Bupropion's side effects

  • Carbamazepine, efavirenz, phenobarbital, phenytoin, rifampin, or ritonavir because they may decrease Bupropion's effectiveness

  • Antiarrhythmics (eg, flecainide, propafenone), beta-blockers (eg, metoprolol), phenothiazines (eg, thioridazine), selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), or tricyclic antidepressants (eg, nortriptyline) because the risk of their side effects may be increased by Bupropion

  • Tamoxifen because its effectiveness may be decreased by Bupropion, which may lead to an increased risk of breast cancer recurrence in women with a history of breast cancer

This may not be a complete list of all interactions that may occur. Ask your health care provider if Bupropion may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Bupropion:


Use Bupropion as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Bupropion comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Bupropion refilled.

  • Take Bupropion by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

  • Several weeks may pass before your symptoms improve. Do not stop taking Bupropion without checking with your doctor.

  • Take your doses at the same times each day, at least 6 hours apart unless directed otherwise by your doctor. This may help to decrease the risk of seizures with Bupropion.

  • Continue to take Bupropion even if you feel well. Do not miss any doses.

  • If you miss a dose of Bupropion, skip the missed dose and go back to your regular dosing schedule. Do not take more than 1 dose within 6 hours. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Bupropion.



Important safety information:


  • Bupropion may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Bupropion with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are taking Bupropion; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

  • Bupropion may increase your risk of seizures. Your risk may be greater if you also have certain medical conditions, use certain medicines, or if you use a lot of alcohol. Talk to your doctor to see if you may have a greater risk of seizures while taking Bupropion.

  • If you already drink alcohol or use sedatives, do not suddenly stop them without first checking with your doctor. Suddenly stopping them may increase your seizure risk.

  • Do not take decongestants (eg, pseudoephedrine), stimulants, or diet pills while you are taking Bupropion without first checking with your doctor. They may increase your risk of seizures.

  • The risk of seizures may be greater if you take Bupropion in high doses or for a long time. Do NOT take more than the recommended dose, change your dose, or use Bupropion for longer than prescribed without checking with your doctor.

  • Children, teenagers, and young adults who take Bupropion may be at increased risk of suicidal thoughts or actions. Watch all patients who take Bupropion closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.

  • If you have trouble sleeping, you may be taking your dose too close to bedtime. Talk with your doctor about changing your dosing schedule.

  • Bupropion contains the same ingredients as Zyban, a medicine used to help stop smoking, and Aplenzin, another medicine used to treat depression. Do not take Bupropion if you are also taking Zyban or Aplenzin. Discuss any questions or concerns with your doctor.

  • Bupropion may interfere with certain lab tests, including urine screenings for amphetamines. Be sure your doctor and lab personnel know you are taking Bupropion.

  • Use Bupropion with caution in the ELDERLY; they may be more sensitive to its effects.

  • Bupropion should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Bupropion while you are pregnant. Bupropion is found in breast milk. Do not breast-feed while taking Bupropion.


Possible side effects of Bupropion:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Changes in appetite; constipation; dizziness; drowsiness; dry mouth; headache; increased sweating; nausea; nervousness; restlessness; taste changes; trouble sleeping; vomiting; weight changes.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue, unusual hoarseness); blurred vision or other vision changes; changes in sexual desire or ability; chest pain; confusion; dark urine; delusions; fainting; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; hearing problems; menstrual changes; new or worsening mental or mood changes (eg, concentration problems, depression, panic attacks, aggressiveness, agitation, anxiety, impulsiveness, irritability, hostility, exaggerated feeling of well-being, inability to sit still); pale stools; red, swollen, blistered, or peeling skin; seizures; severe headache or dizziness; severe or persistent joint or muscle pain; severe or persistent nausea, vomiting, or stomach pain; severe or persistent nervousness, restlessness, or trouble sleeping; shortness of breath; suicidal thoughts or attempts; tremor; unusual swelling; yellowing of the skin or eyes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Bupropion side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include chest pain; fainting; fast, slow, or irregular heartbeat; fever; hallucinations; loss of consciousness; rigid or painful muscles; seizures; severe dizziness; slow or difficult breathing.


Proper storage of Bupropion:

Store Bupropion at room temperature, between 59 and 77 degrees F (15 and 25 degrees C), in a tight, light-resistant container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Bupropion out of the reach of children and away from pets.


General information:


  • If you have any questions about Bupropion, please talk with your doctor, pharmacist, or other health care provider.

  • Bupropion is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Bupropion. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Bupropion resources


  • Bupropion Side Effects (in more detail)
  • Bupropion Dosage
  • Bupropion Use in Pregnancy & Breastfeeding
  • Drug Images
  • Bupropion Drug Interactions
  • Bupropion Support Group
  • 325 Reviews for Bupropion - Add your own review/rating


  • Bupropion Professional Patient Advice (Wolters Kluwer)

  • Bupropion Prescribing Information (FDA)

  • Aplenzin Consumer Overview

  • Aplenzin Prescribing Information (FDA)

  • Budeprion XL Prescribing Information (FDA)

  • Bupropion Hydrochloride Monograph (AHFS DI)

  • Wellbutrin Prescribing Information (FDA)

  • Wellbutrin Consumer Overview

  • Wellbutrin SR Prescribing Information (FDA)

  • Wellbutrin XL Prescribing Information (FDA)

  • Zyban Prescribing Information (FDA)

  • Zyban Consumer Overview

  • bupropion Advanced Consumer (Micromedex) - Includes Dosage Information



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Cipronatin may be available in the countries listed below.


Ingredient matches for Cipronatin



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