Cruex Prescription Strength Topical

Generic Name: clotrimazole (Topical route)

kloe-TRIM-a-zole

Commonly used brand name(s)

In the U.S.

• Clotrim Antifungal


• Cruex Prescription Strength


• Lotrimin


• Lotrimin AF


• Mycelex

In Canada

• Canesten


• Clotrimaderm


• Desenex


• Myclo-Derm


• Neo-Zol

Available Dosage Forms:

• Lotion


• Solution


• Cream

Therapeutic Class: Antifungal

Chemical Class: Imidazole

Uses For Cruex Prescription Strength

Clotrimazole topical preparations are used to treat fungus infections on the skin.

This medicine is available both over-the-counter (OTC) and with your doctor's prescription.

Before Using Cruex Prescription Strength

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

This medicine has been tested in children and, in effective doses, has not been shown to cause different side effects or problems than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of topical clotrimazole in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Fentanyl


• Tacrolimus


• Trimetrexate

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of clotrimazole

This section provides information on the proper use of a number of products that contain clotrimazole. It may not be specific to Cruex Prescription Strength. Please read with care.

Apply enough clotrimazole to cover the affected and surrounding skin areas, and rub in gently.

Keep this medicine away from the eyes.

When clotrimazole is used to treat certain types of fungus infections of the skin, an occlusive dressing (airtight covering, such as kitchen plastic wrap) should not be applied over the medicine. To do so may cause irritation of the skin. Do not apply an occlusive dressing over this medicine unless you have been directed to do so by your doctor.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment , even if your symptoms begin to clear up after a few days. Since fungus infections may be very slow to clear up, you may have to continue using this medicine every day for several weeks or more. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses .

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For topical dosage forms (cream, lotion, and solution):
  
  • Fungal infections (treatment):
    
    • Adults and children—Use two times a day, morning and evening.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Cruex Prescription Strength

If your skin problem does not improve within 4 weeks, or if it becomes worse, check with your doctor.

Cruex Prescription Strength Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• Skin rash, hives, blistering, burning, itching, peeling, redness, stinging, swelling, or other sign of skin irritation not present before use of this medicine

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Cruex Prescription Strength Topical resources

• Cruex Prescription Strength Topical Use in Pregnancy & Breastfeeding
• Cruex Prescription Strength Topical Support Group
• 2 Reviews for Cruex Prescription Strength Topical - Add your own review/rating

Compare Cruex Prescription Strength Topical with other medications

• Cutaneous Candidiasis
• Tinea Corporis
• Tinea Cruris
• Tinea Pedis
• Tinea Versicolor
• Vaginal Yeast Infection

Sulfatol SS

Generic Name: sulfacetamide sodium and sulfur topical (SUL fa SEET a mide SOE dee um and SUL fur TOP i kal)

Brand Names: Avar Cleanser, Avar Gel, Avar LS Cleanser, Avar-E, Avar-E Emollient, Avar-E Green, Avar-e LS, BP 10-Wash, Clarifoam EF, Clenia Emollient Cream, Clenia Foaming Wash, Plexion , Plexion Cleanser, Plexion Cleansing Cloths, Plexion SCT, Prascion, Prascion Cleanser, Prascion FC Cloths, Prascion RA, Rosac, Rosac Wash, Rosaderm Cleanser, Rosanil Cleanser, Rosula, SE 10-5 SS, Sulfacet-R, Sulfatol C, Sulfatol SS, SulZee Wash, Sumaxin, Sumaxin TS, Sumaxin Wash, Suphera, Topisulf, Zencia Wash, Zetacet

What is Sulfatol SS (sulfacetamide sodium and sulfur topical)?

Sulfacetamide sodium and sulfur are antibiotic that fight bacteria.

The combination of sulfacetamide sodium and sulfur topical (for the skin) is used to treat acne, rosacea, and seborrheic dermatitis (a red, flaking skin rash).

Sulfacetamide sodium and sulfur topical may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Sulfatol SS (sulfacetamide sodium and sulfur topical)?

You should not use this medication if you are allergy to sulfa drugs or if you have kidney disease. Avoid getting this medication in your eyes, nose, or mouth. If this does happen, rinse with water.

Do not cover the treated skin area unless your doctor has told you to.

Avoid using other medications on the areas you treat with sulfacetamide sodium and sulfur topical unless you doctor tells you to.

What should I discuss with my healthcare provider before using Sulfatol SS (sulfacetamide sodium and sulfur topical)?

You should not use this medication if you are allergy to sulfa drugs or if you have kidney disease.

To make sure you can safely use this medication, tell your doctor about all of your medical conditions.

FDA pregnancy category C. It is not known whether sulfacetamide sodium and sulfur topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether sulfacetamide sodium and sulfur topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use Sulfatol SS (sulfacetamide sodium and sulfur topical)?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Wash your hands before and after applying this medication.

Do not cover the treated skin area unless your doctor has told you to.

Use this medication regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Sulfatol SS (sulfacetamide sodium and sulfur topical)?

Avoid getting this medication in your eyes, nose, or mouth. If this does happen, rinse with water. Do not use sulfacetamide sodium and sulfur topical on sunburned, windburned, dry, chapped, irritated, or broken skin.

Avoid using other medications on the areas you treat with sulfacetamide sodium and sulfur topical unless you doctor tells you to.

Sulfatol SS (sulfacetamide sodium and sulfur topical) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

• 
  

  new or worsening skin rash;

  
  


• 
  

  joint pain;

  
  


• 
  

  fever; or

  
  


• 
  

  mouth sores.

  
  

Less serious side effects may include redness, warmth, swelling, itching, stinging, burning, or irritation of treated skin.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Sulfatol SS (sulfacetamide sodium and sulfur topical)?

It is not likely that other drugs you take orally or inject will have an effect on topically applied sulfacetamide sodium and sulfur. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Sulfatol SS resources

• Sulfatol SS Side Effects (in more detail)
• Sulfatol SS Use in Pregnancy & Breastfeeding
• Sulfatol SS Drug Interactions
• 0 Reviews for Sulfatol SS - Add your own review/rating

• Avar LS Cleanser MedFacts Consumer Leaflet (Wolters Kluwer)


• Clarifoam EF Foam MedFacts Consumer Leaflet (Wolters Kluwer)


• Clarifoam EF Prescribing Information (FDA)


• Plexion Prescribing Information (FDA)


• Plexion Cleansing Cloths MedFacts Consumer Leaflet (Wolters Kluwer)


• Plexion SCT Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Plexion TS Emulsion MedFacts Consumer Leaflet (Wolters Kluwer)


• Prascion Cleanser Prescribing Information (FDA)


• Rosac Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Rosaderm Cleanser Prescribing Information (FDA)


• Rosanil Cleanser Prescribing Information (FDA)


• Rosula Foam MedFacts Consumer Leaflet (Wolters Kluwer)


• Rosula Prescribing Information (FDA)


• Rosula Cleanser Emulsion MedFacts Consumer Leaflet (Wolters Kluwer)


• Sumadan MedFacts Consumer Leaflet (Wolters Kluwer)


• Sumadan Wash Prescribing Information (FDA)


• Sumaxin Wash MedFacts Consumer Leaflet (Wolters Kluwer)


• Sumaxin Wash Prescribing Information (FDA)


• Zencia Wash Prescribing Information (FDA)

Compare Sulfatol SS with other medications

• Acne
• Rosacea
• Seborrheic Dermatitis

Where can I get more information?

• Your pharmacist can provide more information about sulfacetamide sodium and sulfur topical.

See also: Sulfatol SS side effects (in more detail)

Capex Shampoo

Pronunciation: floo-oh-SIN-oh-lone
Generic Name: Fluocinolone
Brand Name: Capex

Capex Shampoo is used for:

Treating seborrheic dermatitis (itching, redness, irritation, and flaking) of the scalp. It may also be used for other conditions as determined by your doctor.

Capex Shampoo is a topical corticosteroid. Exactly how it works is unknown.

Do NOT use Capex Shampoo if:

• you are allergic to any ingredient in Capex Shampoo

Contact your doctor or health care provider right away if any of these apply to you.

Before using Capex Shampoo:

Some medical conditions may interact with Capex Shampoo. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have measles, chickenpox, or tuberculosis


• if you have hardening or thinning of the skin or a skin infection


• if you have recently been vaccinated or you have had a positive tuberculin skin test

Some MEDICINES MAY INTERACT with Capex Shampoo. Because little, if any, of Capex Shampoo is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Capex Shampoo may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Capex Shampoo:

Use Capex Shampoo as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Capex Shampoo is for external use only.


• Shake well before each use.


• Rinse hair and scalp completely with water. Apply no more than 1 ounce of Capex Shampoo to the scalp area daily unless otherwise directed by your doctor. Lather and allow the medicine to remain on the scalp for 5 minutes, and then completely rinse hair and scalp twice.


• Do not bandage or wrap the affected area unless directed otherwise by your doctor.


• If you miss a dose of Capex Shampoo, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Capex Shampoo.

Important safety information:

• Avoid contact with eyes. In case of contact, wash eyes liberally with water.


• Capex Shampoo has a corticosteroid in it. Before you start any new medicine, check the label to see if it has a corticosteroid in it too. If it does or if you are not sure, check with your doctor or pharmacist.


• Do NOT use more than the recommended dose or use for longer than prescribed without checking with your doctor.


• Do not use Capex Shampoo for any conditions other than the one for which it was prescribed.


• Talk with your doctor before you receive any vaccine while you are using Capex Shampoo.


• Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use Capex Shampoo.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Capex Shampoo while you are pregnant. It is not known if Capex Shampoo is found in breast milk. If you are or will be breast-feeding while you use Capex Shampoo, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Capex Shampoo:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dryness; itching.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); acne-like rash; excessive hair growth; inflamed hair follicles; inflammation around the mouth; irritation, burning, redness, or swelling not present before using Capex Shampoo; thinning, softening, or discoloration of the skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Capex side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include increased thirst or urination; muscle weakness; unusual weight gain, especially in the face.

Proper storage of Capex Shampoo:

Store Capex Shampoo at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Throw away any unused medicine after 3 months. Do not store in the bathroom. Keep Capex Shampoo out of the reach of children and away from pets.

General information:

• If you have any questions about Capex Shampoo, please talk with your doctor, pharmacist, or other health care provider.


• Capex Shampoo is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Capex Shampoo. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Capex resources

• Capex Side Effects (in more detail)
• Capex Use in Pregnancy & Breastfeeding
• Capex Drug Interactions
• Capex Support Group
• 0 Reviews for Capex - Add your own review/rating

Compare Capex with other medications

• Atopic Dermatitis
• Dermatitis
• Lichen Sclerosus

anti-inhibitor coagulant complex

Generic Name: anti-inhibitor coagulant complex (an TEE in HIB i tor koe AG yoo lant KOM plex)

Brand Names: Autoplex T, Feiba NF, Feiba VH Immuno

What is anti-inhibitor coagulant complex?

Anti-inhibitor coagulant complex is made from proteins normally found in human blood that allow the blood to clot.

Anti-inhibitor coagulant complex is used to treat or prevent bleeding in people with hemophilia A or B and Factor VIII inhibitors.

Anti-inhibitor coagulant complex may also be used for purposes not listed in this medication guide.

What is the most important information I should know about anti-inhibitor coagulant complex?

You should not use anti-inhibitor coagulant complex if you are allergic to it.

Before using this medication, tell your doctor if you have coronary artery disease or a history of heart attack, stroke, or blood clot.

Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

Anti-inhibitor coagulant complex is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

Wear a medical alert tag or carry an ID card stating that you have hemophilia. Any medical care provider who treats you should know that you have a bleeding or blood clotting disorder.

What should I discuss with my healthcare provider before using anti-inhibitor coagulant complex?

You should not use anti-inhibitor coagulant complex if you are allergic to it.

To make sure you can safely use anti-inhibitor coagulant complex, tell your doctor if you have any of these other conditions:

• 
  

  coronary artery disease; or

  
  


• 
  

  history of heart attack, stroke, or blood clot.

  
  

FDA pregnancy category C. It is not known whether anti-inhibitor coagulant complex will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether anti-inhibitor coagulant complex passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Anti-inhibitor coagulant complex is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

How should I use anti-inhibitor coagulant complex?

Anti-inhibitor coagulant complex is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

Anti-inhibitor coagulant complex is usually given once every 6 to 12 hours until your condition improves.

Anti-inhibitor coagulant complex is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medication.

Use a disposable needle only once. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

Wear a medical alert tag or carry an ID card stating that you have hemophilia. Any medical care provider who treats you should know that you have a bleeding or blood clotting disorder. Store anti-inhibitor coagulant complex in a refrigerator. Do not freeze. Take the vial out of the refrigerator and allow it to reach room temperature before mixing with the diluent. Do not heat the medicine. You may store this medicine at room temperature for up to 6 months or until the expiration date on the label. After mixing anti-inhibitor coagulant complex with the diluent, store the mixture at room temperature and use it within 3 hours. Do not refrigerate mixed medicine.

What happens if I miss a dose?

Call your doctor for instructions if you miss a dose of anti-inhibitor coagulant complex.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include some of the serious side effects listed in this medication guide.

What should I avoid while using anti-inhibitor coagulant complex?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Anti-inhibitor coagulant complex side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), feeling like you might pass out;

  
  


• 
  

  fever, chills, runny nose, and drowsiness, followed by rash and joint pain about 2 weeks later;

  
  


• 
  

  sudden numbness or weakness, especially on one side of the body;

  
  


• 
  

  sudden severe headache, confusion, problems with vision, speech, or balance;

  
  


• 
  

  pain, swelling, warmth, or redness in one or both legs;

  
  


• 
  

  chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;

  
  


• 
  

  fast or slow heart rate, weak pulse, trouble breathing, chest pain or cough; or

  
  


• 
  

  nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

  
  

Less serious side effects may include:

• 
  

  pain around the IV needle or

  
  


• 
  

  numbness or tingling, especially in your face.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect anti-inhibitor coagulant complex?

The following drugs should not be given within 12 hours after you receive anti-inhibitor coagulant complex.

• 
  

  aminocaproic acid (Amicar);

  
  


• 
  

  desmopressin (DDAVP); or

  
  


• 
  

  tranexamic acid (Cyklokapron, Lysteda).

  
  

This list is not complete and other drugs may interact with anti-inhibitor coagulant complex. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More anti-inhibitor coagulant complex resources

• Anti-inhibitor coagulant complex Side Effects (in more detail)
• Anti-inhibitor coagulant complex Use in Pregnancy & Breastfeeding
• Anti-inhibitor coagulant complex Drug Interactions
• Anti-inhibitor coagulant complex Support Group
• 0 Reviews for Anti-inhibitor coagulant complex - Add your own review/rating

• anti-inhibitor coagulant complex Intravenous Advanced Consumer (Micromedex) - Includes Dosage Information


• Anti-Inhibitor Coagulant Complex Professional Patient Advice (Wolters Kluwer)


• Anti-inhibitor Coagulant Complex Monograph (AHFS DI)


• Anti-Inhibitor Coagulant Complex MedFacts Consumer Leaflet (Wolters Kluwer)


• FEIBA NF Prescribing Information (FDA)

Compare anti-inhibitor coagulant complex with other medications

• Hemophilia A

Where can I get more information?

• Your doctor or pharmacist can provide more information about anti-inhibitor coagulant complex.

See also: anti-inhibitor coagulant complex side effects (in more detail)

Amdry-C

Generic Name: chlorpheniramine, methscopolamine, and pseudoephedrine (KLOR fen IR a meen, METH skoe POL a meen, SOO doe ee FED rin)

Brand Names: AllePak, Allergy AM-PM Dose Pack, Allergy DN, Amdry-C, Durahist, Hista-Vent PSE, PCM-LA, Pseudo CM TR, Rhinaclear, Time-Hist QD, VisRx Dose Pack

What is Amdry-C (chlorpheniramine, methscopolamine, and pseudoephedrine)?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Methscopolamine reduces the secretions of certain organs in the body.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of chlorpheniramine, methscopolamine, and pseudoephedrine is used to treat symptoms of the common cold or seasonal allergies, including sneezing, runny or stuffy nose, and itchy, watery eyes.

Chlorpheniramine, methscopolamine, and pseudoephedrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Amdry-C (chlorpheniramine, methscopolamine, and pseudoephedrine)?

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use a cough or cold if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Do not use this medication if you are allergic to chlorpheniramine or methscopolamine, or if you have severe high blood pressure or coronary artery disease, narrow-angle glaucoma, a stomach ulcer, or if you are unable to urinate.

Do not use this medication during an asthma attack.

Avoid drinking alcohol while you are taking this medication.

What should I discuss with my healthcare provider before taking Amdry-C (chlorpheniramine, methscopolamine, and pseudoephedrine)?

Do not use a cough or cold if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Dangerous side effects may occur if you take a cough or cold medicine before the MAO inhibitor has cleared from your body. Do not use this medication if you are allergic to chlorpheniramine, methscopolamine, or pseudoephedrine, or if you have:

• 
  

  severe or uncontrolled high blood pressure;

  
  


• 
  

  severe coronary artery disease;

  
  


• 
  

  narrow angle glaucoma;

  
  


• 
  

  a stomach ulcer;

  
  


• 
  

  if you are unable to urinate; or

  
  


• 
  

  if you are having an asthma attack.

  
  

Before using chlorpheniramine, methscopolamine, and pseudoephedrine, tell your doctor if you are allergic to any drugs, or if you have:

• kidney disease;


• liver disease;


• 
  

  diabetes;

  
  


• 
  

  glaucoma;

  
  


• 
  

  heart disease, high blood pressure, or circulation problems;

  
  


• 
  

  overactive thyroid;

  
  


• 
  

  a seizure disorder such as epilepsy;

  
  


• 
  

  asthma, emphysema or chronic bronchitis; or

  
  


• 
  

  urination problems or an enlarged prostate.

  
  

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Chlorpheniramine, methscopolamine, and pseudoephedrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Amdry-C (chlorpheniramine, methscopolamine, and pseudoephedrine)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the instructions on your prescription label. Cold medicine is usually taken for only a short time until your symptoms clear up.

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Take this medicine with a full glass of water. Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Contact your doctor if your symptoms do not improve or if they get worse while using this medication.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are taking an antihistamine.

Store chlorpheniramine, methscopolamine, and pseudoephedrine at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include nausea, vomiting, severe drowsiness, shallow breathing, ringing in your ears, problems with balance or coordination, hallucinations (seeing things), sleep problems (insomnia), feeling restless or excited, blurred vision, tremors, flushed face, and seizure (convulsions).

What should I avoid while taking Amdry-C (chlorpheniramine, methscopolamine, and pseudoephedrine)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid becoming overheated in hot weather. Chlorpheniramine, methscopolamine, and pseudoephedrine increases the risk of heat stroke because it causes decreased sweating and can make you more sensitive to sunlight.

Avoid drinking alcohol. It can increase some of the side effects of chlorpheniramine, methscopolamine, and pseudoephedrine. Narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by chlorpheniramine or methscopolamine. Tell your doctor if you regularly use any of these medicines, or any other cold or allergy medications.

Amdry-C (chlorpheniramine, methscopolamine, and pseudoephedrine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

• 
  

  numbness, tingling, or cold feeling in your hands or feet;

  
  


• 
  

  fast, pounding, or uneven heart beats;

  
  


• 
  

  painful or difficult urination;

  
  


• 
  

  confusion, hallucinations, unusual thoughts or behavior;

  
  


• 
  

  feeling short of breath;

  
  


• 
  

  tremors or shaking; or

  
  


• 
  

  severe drowsiness, feeling light-headed, fainting.

  
  

Less serious side effects may include:

• 
  

  dry mouth, stomach pain, changes in appetite;

  
  


• 
  

  drowsiness, dizziness, weakness, headache;

  
  


• 
  

  dry eyes, blurred vision;

  
  


• 
  

  increased sweating;

  
  


• 
  

  skin rash; or

  
  


• 
  

  feeling nervous or excited (especially in children).

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Amdry-C (chlorpheniramine, methscopolamine, and pseudoephedrine)?

Many drugs can interact with chlorpheniramine, methscopolamine, and pseudoephedrine. Below is just a partial list. Tell your doctor if you are using any of these drugs:

• 
  

  antacids;

  
  


• 
  

  medicine to treat diarrhea (such as Immodium, Kaopectate, Pepto-Bismol);

  
  


• 
  

  atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);

  
  


• 
  

  bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);

  
  


• 
  

  glycopyrrolate (Robinul);

  
  


• 
  

  mepenzolate (Cantil);

  
  


• 
  

  bladder or urinary medications such as darifenacin (Enablex), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);

  
  


• 
  

  irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine);

  
  


• 
  

  a beta-blocker such as atenolol (Tenormin), bisoprolol (Zebeta, Ziac), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), timolol (Blocadren), and others;

  
  


• 
  

  a barbiturate such as phenobarbital (Luminal, Solfoton); or

  
  


• 
  

  an antidepressant such as amitriptyline (Elavil, Etrafon), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Janimine, Tofranil), and others.

  
  

This list is not complete and there may be other drugs that can interact with chlorpheniramine, methscopolamine, and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Amdry-C resources

• Amdry-C Use in Pregnancy & Breastfeeding
• Drug Images
• Amdry-C Drug Interactions
• Amdry-C Support Group
• 0 Reviews for Amdry-C - Add your own review/rating

• Dallergy PSE Sustained-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• DryMax Syrup MedFacts Consumer Leaflet (Wolters Kluwer)


• VisRx Dose Pack Prescribing Information (FDA)

Compare Amdry-C with other medications

• Hay Fever
• Nasal Congestion
• Sinus Symptoms

Where can I get more information?

• Your pharmacist can provide more information about chlorpheniramine, methscopolamine, and pseudoephedrine written for health professionals that you may read.

mitoxantrone Intravenous, Injection

mye-toe-ZAN-trone

Intravenous route(Solution)

Mitoxantrone should be given slowly into a freely flowing IV infusion and must never be given subQ, IM, or intra-arterially. Not for intrathecal use; severe injury with permanent sequelae can result from intrathecal administration. Except for the treatment of acute nonlymphocytic leukemia, therapy generally should not be given to patients with baseline neutrophil counts of less than 1500 cells/mm(3). Cardiotoxicity, potentially fatal, has been associated with treatment. Presence or history of cardiovascular disease, prior or concomitant radiotherapy to the mediastinal/pericardial area, previous therapy with other anthracyclines or anthracenediones, or concomitant use of other cardiotoxic drugs may increase the risk of cardiac toxicity. Monitor cardiac function (cardiac signs/symptoms and left ventricular ejection fraction (LVEF)) in all patients during therapy. Patients with multiple sclerosis (MS) who have a baseline LVEF below the lower limit of normal should not receive mitoxantrone. Monitor MS patients for cardiac function prior to each dose. Do not give additional doses if clinically significant drop in LVEF during treatment and do not administer a cumulative dose greater than 140 mg/m(2) in MS patients. When mitoxantrone therapy is withdrawn, late-occurring cardiotoxicity should be evaluated on an annual basis in MS patients. Mitoxantrone therapy in MS patients and in cancer patients increases the risk of developing secondary acute myeloid leukemia .

Commonly used brand name(s)

In the U.S.

• Novantrone


• OTN Mitoxantrone

Available Dosage Forms:

• Solution

Therapeutic Class: Antineoplastic Agent

Uses For mitoxantrone

Mitoxantrone injection is used alone or together with other medicines to treat advanced prostate cancer and acute nonlymphocytic leukemia (ANLL). It belongs to the group of medicines known as antineoplastics or cancer medicines. Mitoxantrone is also used to treat some forms of multiple sclerosis (MS). mitoxantrone will not cure MS, but it may extend the time between relapses.

Mitoxantrone interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by mitoxantrone, other unwanted effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some unwanted effects may not occur for months or years after the medicine is used.

Before you begin treatment with mitoxantrone, you and your doctor should talk about the good mitoxantrone will do as well as the risks of using it.

mitoxantrone is to be administered only by or under the immediate supervision of your doctor.

Before Using mitoxantrone

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For mitoxantrone, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to mitoxantrone or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of mitoxantrone injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of mitoxantrone injection in the elderly. However, elderly patients are more likely to have age-related medical problems, which may require caution in patients receiving mitoxantrone.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	D	Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving mitoxantrone, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using mitoxantrone with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Rotavirus Vaccine, Live

Using mitoxantrone with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Adenovirus Vaccine Type 4, Live


• Adenovirus Vaccine Type 7, Live


• Bacillus of Calmette and Guerin Vaccine, Live


• Influenza Virus Vaccine, Live


• Measles Virus Vaccine, Live


• Mumps Virus Vaccine, Live


• Rotavirus Vaccine, Live


• Rubella Virus Vaccine, Live


• Smallpox Vaccine


• Typhoid Vaccine


• Valspodar


• Varicella Virus Vaccine


• Yellow Fever Vaccine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of mitoxantrone. Make sure you tell your doctor if you have any other medical problems, especially:

• Blood clots or bleeding problems or


• Blood disease (e.g., anemia, low white blood cell counts) or


• Bone marrow depression or


• Congestive heart failure or


• Heart or blood vessel disease—May cause side effects to become worse.

• Chickenpox (including recent exposure) or


• Herpes zoster (shingles) or


• Infections—There is an increased risk of severe infections affecting other parts of the body.

• Gout, history of or


• Kidney stones—May make these conditions worse.

• Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of mitoxantrone

Mitoxantrone is sometimes given together with certain other medicines. If you are using a combination of medicines, it is important that you receive each one at the proper time. If you are taking some of these medicines by mouth, ask your doctor to help you plan a way to take them at the right times.

A nurse or other trained health professional will give you mitoxantrone in a hospital or cancer clinic. mitoxantrone is given through a needle placed in one of your veins.

If you have pain, burning, redness, or swelling of your skin area where the needle is placed, tell your doctor or nurse right away.

If mitoxantrone gets on your skin, rinse the area well with warm water and tell your doctor. If the medicine gets in your eyes, rinse your eyes with large amounts of water, and tell your doctor.

While you are receiving mitoxantrone, your doctor may want you to drink extra fluids so you will pass more urine. This will help prevent kidney problems and keep your kidneys working well.

Mitoxantrone often causes nausea and vomiting. However, it is very important that you continue to receive the medicine, even if your stomach is upset. Ask your doctor for ways to lessen these effects.

mitoxantrone comes with a patient package insert. Read and follow the information carefully. Ask your doctor if you have any questions.

Precautions While Using mitoxantrone

It is very important that your doctor check your progress at regular visits to make sure that mitoxantrone is working properly. Blood tests and tests for your heart function may be needed to check for unwanted effects.

You should not receive mitoxantrone if you are pregnant. Using mitoxantrone while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away. Also, your doctor may require you to have a pregnancy test before you receive each dose of mitoxantrone, to make sure you are not pregnant.

Check with your doctor right away if you are having chest pain or discomfort; fast or irregular heartbeats; shortness of breath; swelling of the feet and lower legs; or troubled breathing. These could be symptoms of a serious heart problem.

mitoxantrone may change the color of your urine to a bluish-green color. The whites of your eyes may also appear slightly bluish-green. This is normal, especially within the first 24 hours after you receive the medicine.

While you are being treated with mitoxantrone, and after you stop treatment with it, do not have any immunizations (vaccines) without your doctor's approval. Mitoxantrone may lower your body's resistance and there is a chance you might get the infection the immunization is meant to prevent. In addition, other persons living in your household should not receive live virus vaccines (eg, nasal flu vaccine, measles, mumps, or rubella) since there is a chance they could pass the virus to you. Also, avoid persons who have received live virus vaccines. Do not get close to them and do not stay in the same room with them for very long. If you cannot take these precautions, you should consider wearing a protective face mask that covers the nose and mouth.

Mitoxantrone can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:

• If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.


• Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in the urine or stools; or pinpoint red spots on your skin.


• Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done.


• Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime.


• Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters.


• Avoid contact sports or other situations where bruising or injury could occur.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

mitoxantrone Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

• Black, tarry stools


• bladder pain


• bloody or cloudy urine


• cough or shortness of breath


• difficult, burning, or painful urination


• dizziness


• fainting


• fast, slow, or irregular heartbeat


• frequent urge to urinate


• lower back or side pain


• pale skin


• stomach pain


• swelling or inflammation of the mouth


• troubled breathing with exertion


• ulcers, sores, or white spots in the mouth


• unusual bleeding or bruising


• unusual tiredness or weakness

Less common

• Blood in the urine or stools


• decrease in urination


• fever or chills


• pinpoint red spots on the skin


• seizures


• sore, red eyes


• swelling of the feet and lower legs


• yellow eyes or skin

Rare

• Blue skin at the place of injection


• pain or redness at the place of injection


• skin rash

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Absent, missed, or irregular menstrual periods


• back pain


• body aches or pains


• congestion


• constipation


• diarrhea


• dryness or soreness of the throat


• hair loss


• headache


• longer or heavier menstrual periods


• nausea or vomiting


• oral bleeding


• pain or tenderness around the eyes and cheekbones


• runny nose


• sneezing


• stopping of menstrual bleeding


• stuffy nose


• tender, swollen glands in the neck


• thinning of the hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: mitoxantrone Intravenous, Injection side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More mitoxantrone Intravenous, Injection resources

• Mitoxantrone Intravenous, Injection Side Effects (in more detail)
• Mitoxantrone Intravenous, Injection Use in Pregnancy & Breastfeeding
• Mitoxantrone Intravenous, Injection Drug Interactions
• Mitoxantrone Intravenous, Injection Support Group
• 1 Review for Mitoxantrone Intravenous, Injection - Add your own review/rating

Compare mitoxantrone Intravenous, Injection with other medications

• Acute Nonlymphocytic Leukemia
• Multiple Sclerosis
• Non-Hodgkin's Lymphoma
• Prostate Cancer

Nicardipine Sustained-Release Capsules

Pronunciation: nye-KAR-di-peen
Generic Name: Nicardipine
Brand Name: Cardene SR

Nicardipine Sustained-Release Capsules are used for:

Treating high blood pressure. It may be used alone or in combination with other high blood pressure medicines. It may also be used for other conditions as determined by your doctor.

Nicardipine Sustained-Release Capsules are a calcium channel blocker. It works by relaxing the blood vessels, which helps to lower blood pressure.

Do NOT use Nicardipine Sustained-Release Capsules if:

• you are allergic to any ingredient in Nicardipine Sustained-Release Capsules


• you are breast-feeding


• you have advanced narrowing of your aorta (stenosis)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Nicardipine Sustained-Release Capsules:

Some medical conditions may interact with Nicardipine Sustained-Release Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant or planning to become pregnant


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have angina (chest pain), congestive heart failure (CHF) or other heart problems, adrenal glad problems (eg, pheochromocytoma), liver or kidney problems, low blood pressure, or lung congestion associated with heart attack, or have had a stroke


• you have CHF and you are taking a beta-blocker, or you are having beta-blocker withdrawal

Some MEDICINES MAY INTERACT with Nicardipine Sustained-Release Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Cimetidine because it may increase the risk of Nicardipine Sustained-Release Capsules's side effects


• Cyclosporine or digoxin because the risk of their side effects may be increased by Nicardipine Sustained-Release Capsules

This may not be a complete list of all interactions that may occur. Ask your health care provider if Nicardipine Sustained-Release Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Nicardipine Sustained-Release Capsules:

Use Nicardipine Sustained-Release Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Nicardipine Sustained-Release Capsules by mouth with or without food, but do not take with a high-fat meal.


• Swallow Nicardipine Sustained-Release Capsules whole. Do not break, crush, or chew before swallowing.


• Do not eat grapefruit or drink grapefruit juice while taking Nicardipine Sustained-Release Capsules unless your doctor directs you otherwise.


• If you miss a dose of Nicardipine Sustained-Release Capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Nicardipine Sustained-Release Capsules.

Important safety information:

• Nicardipine Sustained-Release Capsules may cause dizziness or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use Nicardipine Sustained-Release Capsules with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Patients being treated for high blood pressure often feel tired or run down for a few weeks after beginning therapy. Continue taking your medicine even though you may not feel quite "normal." Contact your doctor or pharmacist about any new symptoms.


• Maximum lowering of blood pressure occurs approximately 1 to 2 hours after taking the medicine. Blood pressure should be taken 1 to 2 hours after the medicine has been taken.


• Tell your doctor or dentist that you take Nicardipine Sustained-Release Capsules before you receive any medical or dental care, emergency care, or surgery.


• Additional monitoring of your dose or condition may be necessary if you are using intravenous (IV) calcium.


• Lab tests, including blood pressure, electrocardiogram (ECG) readings, and monitoring of heart rate, may be performed while you use Nicardipine Sustained-Release Capsules. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nicardipine Sustained-Release Capsules while you are pregnant. Nicardipine Sustained-Release Capsules are found in breast milk. Do not breast-feed while taking Nicardipine Sustained-Release Capsules.

If you suddenly stop taking Nicardipine Sustained-Release Capsules, you may experience WITHDRAWAL symptoms including increased chest pain (angina) and more frequent chest pain.

Possible side effects of Nicardipine Sustained-Release Capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; headache; nausea; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); calf pain, swelling, or redness; confusion; fainting; fast or irregular heartbeat; fever; increased chest pain; pounding in the chest; shortness of breath or wheezing; swelling of the feet, ankles, or hands; unusual bruising or bleeding.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Nicardipine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; drowsiness; fast or slowed heart rate; flushing; slurred speech; weakness.

Proper storage of Nicardipine Sustained-Release Capsules:

Store Nicardipine Sustained-Release Capsules between 59 and 86 degrees F (15 and 30 degrees C) in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Nicardipine Sustained-Release Capsules out of the reach of children and away from pets.

General information:

• If you have any questions about Nicardipine Sustained-Release Capsules, please talk with your doctor, pharmacist, or other health care provider.


• Nicardipine Sustained-Release Capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Nicardipine Sustained-Release Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Nicardipine resources

• Nicardipine Side Effects (in more detail)
• Nicardipine Use in Pregnancy & Breastfeeding
• Drug Images
• Nicardipine Drug Interactions
• Nicardipine Support Group
• 0 Reviews for Nicardipine - Add your own review/rating

Compare Nicardipine with other medications

• Angina Pectoris Prophylaxis
• Heart Failure
• High Blood Pressure

Radiologic agents

See also

• radiologic adjuncts
  • cardiac stressing agents
  • radiologic conjugating agents

Drug List:

Dentinox Infant Colic Drops

1. Name Of The Medicinal Product

Dentinox Infant Colic Drops

2. Qualitative And Quantitative Composition

Activated Dimeticone 42.00 mg/5ml

For excipients, see 6.1

3. Pharmaceutical Form

Oral suspension

Translucent white liquid

4. Clinical Particulars

4.1 Therapeutic Indications

For the gentle relief of wind and griping pains in infants, caused by the accumulation of ingested air. Facilitates eructation. Can be used from birth onwards.

4.2 Posology And Method Of Administration

2½ ml (one measured dose of the syringe) with or after each feed. May be added to the infant's bottle or given orally directly from the syringe. Maximum 6 doses per day. For infants can be used from birth onwards.

4.3 Contraindications

Hypersensitivity to the active substances or to any of the excipients

Contains sucrose. Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.

4.4 Special Warnings And Precautions For Use

Keep all medicines out of the reach of children.

If symptoms persist obtain medical advice.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

None known..

4.6 Pregnancy And Lactation

Not applicable.

4.7 Effects On Ability To Drive And Use Machines

Not applicable.

4.8 Undesirable Effects

None known.

4.9 Overdose

From the literature it would appear that all the silicone will be excreted unchanged and that there was no increase of urinary silicate output or of absorption of the silicone.

It was concluded that the Activated Dimeticone carried no significant carcinogenic hazard, and that no other significant toxic effect attributable to Activated Dimeticone has been observed.

Overdosage may prove a problem with diabetics because of the sugar content.

5. Pharmacological Properties

5.1 Pharmacodynamic Properties

Excessive swallowing of air results in collection of gas in the intestine. This can be the result of too rapid eating, excessive use of a pacifier (dummy), finger sucking or yelling. When the swallowed air is in the intestine, bubbles are formed, which makes it more difficult for the gas to pass through the intestine canal, resulting in abdominal distension and pain. Activated Dimeticone is a surface active substance which changes the surface tension of the intestinal mucus. Thus, the air bubbles burst and the gas is released. The elimination of the gas, air or foam from the gastro-intestinal tract, relieves abdominal distension and dyspepsia.

5.2 Pharmacokinetic Properties

Activated Dimeticone is chemically inert and is not absorbed. Its effect is local on the intestinal contents.

No side effects from the substance are reported from the literature.

From the toxicity trials undertaken by Dow Corning, it has been demonstrated in the rat that all the Dimeticone was recovered in the faeces and that there was no increase in urinary salicate output.

In four human subjects given 376.5mg of Activated Dimeticone, twice daily for 10 days, it was found that there was no increase in their urinary silicate output and no evidence of absorption of the silicone.

5.3 Preclinical Safety Data

There are no pre-clinical data of relevance to the prescriber which are additional to that already included in other sections of the SPC

6. Pharmaceutical Particulars

6.1 List Of Excipients

Purified Water , Sucrose , Carbomer , Dill Oil, Sodium Hydroxide , Nipasept [Methylhydroxybenzoate, Ethylhydroxybenzoate, Propylhydroxybenzoate].

6.2 Incompatibilities

None known.

6.3 Shelf Life

2 years

6.4 Special Precautions For Storage

Do not store above 25 ºC.

6.5 Nature And Contents Of Container

Pack size 100ml

100ml - HDPE round bottle with a jay cap tamper evident closure, with 2.5ml oral dosing syringe.

Pack size 2.5ml

Sample sachets:

40gsm craft paper, 10 gsm polyethylene, 8gsm aluminium foil and 30gsm surlyn.

6.6 Special Precautions For Disposal And Other Handling

After use, rinse the syringe with warm water and dry.

ADMINISTRATION DETAILS

7. Marketing Authorisation Holder

DDD Limited,

94, Rickmansworth Road

Watford

Hertfordshire, WD18 7JJ.

8. Marketing Authorisation Number(S)

PL 0133/0022

9. Date Of First Authorisation/Renewal Of The Authorisation

Date of first authorisation: 29^th November 1976

Date of last renewal: 9^th September 2008

10. Date Of Revision Of The Text

July 2009

Kava

Pronunciation: Not applicable.
Generic Name: Kava
Brand Name: Generics only. No brands available.

Infrequent (possibly fatal) liver disease may occur with use of kava products. Stop using kava and seek immediate medical attention if you develop severe nausea, extreme fatigue, stomach pain, dark urine, or yellowing of the skin, eyes, or nails.

Kava is used for:

Nervousness, trouble sleeping, hot flashes due to menopause, and as a muscle relaxant. Some herbal/diet supplement products have been found to contain possibly harmful impurities/additives. It may have other uses as well. Check with your pharmacist for more details regarding the particular brand you use.

Kava is an herbal product. It is thought to work by mildly sedating the central nervous system.

Do NOT use Kava if:

• you are allergic to any ingredient in Kava


• you are pregnant or breast-feeding

Contact your doctor or health care provider right away if any of these apply to you.

Before using Kava:

Some medical conditions may interact with Kava. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are planning to become pregnant


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have liver problems or a history of depression

Some MEDICINES MAY INTERACT with Kava. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Benzodiazepines (eg, alprazolam) because side effects may be increased by Kava

This may not be a complete list of all interactions that may occur. Ask your health care provider if Kava may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Kava:

Use Kava as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• This product may be taken with or without food.


• Dosing depends on the use and the source of the product.


• Use as directed on the package, unless instructed otherwise by your doctor.


• If you miss taking a dose of Kava for 1 or more days, there is no cause for concern. If your doctor recommended that you take it, try to remember your dose every day.

Ask your health care provider any questions you may have about how to use Kava.

Important safety information:

• Do not exceed the recommended dose or take this product for longer than 3 months without checking with your doctor.


• Long-term, continuous use of kava may cause red eyes or scaly skin. These are temporary, but the use of kava must be stopped.


• This product has not been approved by the Food and Drug Administration (FDA) as safe and effective for any medical condition. The long-term safety of herbal products is not known. Before using any alternative medicine, talk with your doctor or pharmacist.


• This product is not recommended for use in CHILDREN younger than 18 years of age.


• PREGNANCY and BREAST-FEEDING: Do not use this product if you are pregnant. Do not breast-feed while using this product.

Possible side effects of Kava:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine; changes in vision; enlarged pupils; lack of coordination; muscle weakness; puffy face; red eyes; shortness of breath; weight loss.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Kava side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blood in urine; difficulty moving; severe muscle weakness; shortness of breath; tiredness; unusual drowsiness.

Proper storage of Kava:

Store at room temperature away from heat, moisture, and light unless otherwise directed on the package label. Do not store in the bathroom. Most herbal products are not in childproof containers. Keep Kava out of the reach of children and away from pets.

General information:

• If you have any questions about Kava, please talk with your doctor, pharmacist, or other health care provider.


• Kava is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Kava. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Kava resources

• Kava Side Effects (in more detail)
• Kava Use in Pregnancy & Breastfeeding
• Kava Drug Interactions
• Kava Support Group
• 1 Review for Kava - Add your own review/rating

• Kava Natural MedFacts for Professionals (Wolters Kluwer)


• Kava Natural MedFacts for Consumers (Wolters Kluwer)


• kava Concise Consumer Information (Cerner Multum)

Compare Kava with other medications

• Anxiety
• Anxiety and Stress
• Herbal Supplementation

Optrex Sore Eye Drops

1. Name Of The Medicinal Product

Optrex Sore Eye Drops

2. Qualitative And Quantitative Composition

Active

Distilled Witch Hazel BPC l3%v/v

(Synonyms: Hamamelis Water, Witch Hazel)

3. Pharmaceutical Form

Eye Drops

4. Clinical Particulars

4.1 Therapeutic Indications

For the relief of minor eye irritations caused by dusty or smoky atmospheres, driving or close work.

4.2 Posology And Method Of Administration

For topical application into the eye.

For adults, children and the elderly:

Gently squeeze one or two drops into each eye.

Use as often as required.

4.3 Contraindications

Hypersensitivity to any of the ingredients.

4.4 Special Warnings And Precautions For Use

For external use only.

Not suitable for use with hydrophilic (soft) contact lenses.

Keep all medicines out of the sight and reach of children.

Discard any eye drops remaining 28 days after opening the container.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

No clinically significant drug interactions known.

4.6 Pregnancy And Lactation

The safety of Optrex Sore Eyes Eye Drops during pregnancy and lactation has not been established but use during these periods is not considered to constitute a hazard.

4.7 Effects On Ability To Drive And Use Machines

No adverse effects known.

4.8 Undesirable Effects

Occasional hypersensitivity reactions.

4.9 Overdose

In view of the size of the container, overdosage should not be a problem and any treatment should only be symptomatic.

5. Pharmacological Properties

5.1 Pharmacodynamic Properties

Hamamelis water has cooling and astringent properties.

5.2 Pharmacokinetic Properties

Not available.

5.3 Preclinical Safety Data

There are no preclinical safety data of relevance to the consumer.

6. Pharmaceutical Particulars

6.1 List Of Excipients

Boric acid

Borax

Glycerin

Benzalkonium chloride

Purified water

6.2 Incompatibilities

Not applicable.

6.3 Shelf Life

a)	Unopened:	36 months
b)	After first opening:	28 days

6.4 Special Precautions For Storage

Store below 25°C.

6.5 Nature And Contents Of Container

Polyethylene bottle with a polyethylene dropper plug and a tamper evident polyethylene cap. Pack sizes of 10ml and 18ml.

6.6 Special Precautions For Disposal And Other Handling

None.

ADMINISTRATIVE DATA

7. Marketing Authorisation Holder

Optrex Limited

1 Thane Road West

Nottingham

NG2 3AA

8. Marketing Authorisation Number(S)

PL 00062/5003R

9. Date Of First Authorisation/Renewal Of The Authorisation

15 May 1987

10. Date Of Revision Of The Text

15/04/2008